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WANIDA > Projects > ARISE Project: Innovative vector control strategies for sustainable control of malaria and dengue mosquito vectors

Project title:
ARISE Project: Innovative vector control strategies for sustainable control of malaria and dengue mosquito vectors.

Principal Investigator:
Dr. Etienne BILGO, Research Fellow
Contact: bilgo02@yahoo.fr

WANIDA > Projects > ARISE Project: Innovative vector control strategies for sustainable control of malaria and dengue mosquito vectors

Innovative and complementary vector control methods and strategies are urgently needed for malaria, dengue and other vector-borne diseases (VBDs) in Africa.
In Burkina Faso, we have recently characterized local strains of entomopathogenic fungi (Metarhizium pingshaense) that have shown unprecedented virulence and entomopathogenicity against mosquitoes.

Thus, these results lay the foundation for innovative strategies on the use of fungi for safe and reliable control of MTV.
However, several fundamental and applied questions remain regarding the practical use of these fungi in vector control. In this research project we are primarily addressing four main questions:

 1) What are the molecular, biochemical, and physiological bases that govern fungal infection in mosquitoes.

 2) Can these fungal strains be used in synergy with current vector control tools (i.e. chemical insecticides)? 

3) Could Metarhizum strains be combined with other emerging vector control strategies, e.g. Wolbachia for dengue virus control?

4) Finally, what are the expectations and concerns of local communities regarding fungus-based strategies for malaria and dengue control?

Using a combination of classical and novel approaches, we will investigate the practical utility of one or more strains of Metarhizium from Burkina in malaria and dengue vector control.

The ultimate goal of this research project is to develop local isolates of entomopathogenic fungi that will become part of the arsenal of vector control tools in the coming years. Finally, the ARISE project will also contribute to the training of at least three PhD students and six masters students on emerging biotechnologies in the context of vector control.

Host structure:
African Center of Excellence in Biotechnological Innovations for the Elimination of Vector-borne Diseases (CEA/ITECH-MTV) / Institut de Recherche en Sciences de la Santé (IRSS).

Partner structures :

  • Ace Partner/WANIDA-IRD
  • Muraz Center (BFA)
  • University of Ghana (GH)
  • University of Glasgow (UK)
  • University of Maryland (USA)

Project duration: November 2023 – September 2027

Funder: African Academy of Sciences (AAS) and European Union

Principal Investigator :
Dr. Etienne BILGO, Research Fellow
Contact: bilgo02@yahoo.fr

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