{"id":395,"date":"2021-10-13T16:55:30","date_gmt":"2021-10-13T14:55:30","guid":{"rendered":"https:\/\/acepartnerz.kinsta.cloud\/wanida\/?post_type=projet&p=395"},"modified":"2022-10-08T12:15:43","modified_gmt":"2022-10-08T10:15:43","slug":"sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria","status":"publish","type":"projet","link":"https:\/\/ace-partner.org\/wanida\/projet\/sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria\/","title":{"rendered":"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria"},"content":{"rendered":"\n


Contexte <\/strong>:
Le SARS-CoV-2 est extr\u00eamement virulent, comme ses pr\u00e9d\u00e9cesseurs SARS-CoV et MERS-CoV, qui ont d\u00e9clench\u00e9 des \u00e9pid\u00e9mies en 2003 et 2012. La transmission du SARS-CoV-2 en Afrique \u00e9tait initialement lente, avec peu de cas signal\u00e9s en Egypte suite \u00e0 sa premi\u00e8re apparition le 14 f\u00e9vrier 2020.
Dans la plupart des pays africains, de nombreux observateurs ont attribu\u00e9 le faible taux d’incidence enregistr\u00e9 de COVID-19 au sous-diagnostic. La maladie s’est propag\u00e9e rapidement \u00e0 travers le monde et l’OMS a d\u00e9clar\u00e9 la maladie \u00e0 coronavirus 2019 (COVID-19) une pand\u00e9mie le 24 f\u00e9vrier 2020.<\/p>\n\n\n\n

Bien que des initiatives de sant\u00e9 publique telles que la vaccination et la quarantaine aient \u00e9t\u00e9 adopt\u00e9es \u00e0 l’\u00e9chelle mondiale, les morbidit\u00e9s et mortalit\u00e9s associ\u00e9es \u00e0 la COVID-19 demeure une menace pour la sant\u00e9 et la croissance \u00e9conomique. La p\u00e9nurie mondiale de tests de diagnostic, en particulier d’\u00e9couvillons pour la collecte d’\u00e9chantillons respiratoires, la pr\u00e9valence de r\u00e9sultats faussement n\u00e9gatifs et l’incapacit\u00e9 \u00e0 effectuer des tests rapides et en vrac pour les admissions \u00e0 l’h\u00f4pital soulignent la n\u00e9cessit\u00e9 de d\u00e9velopper des m\u00e9thodes de test alternatives. <\/p>\n\n\n\n

Les tests s\u00e9rologiques COVID-19 sont largement ax\u00e9s sur l’identification d’anticorps uniques contre les antig\u00e8nes du SARS-CoV-2. Les IgM sont les premiers anticorps \u00e0 appara\u00eetre en r\u00e9ponse \u00e0 l’exposition initiale d’un antig\u00e8ne, tandis que les IgG apparaissent plus tard et sont plus sp\u00e9cifiques \u00e0 l’antig\u00e8ne. Les tests s\u00e9rologiques peuvent confirmer les r\u00e9sultats du diagnostic mol\u00e9culaire ou reconna\u00eetre les individus infect\u00e9s qui sont n\u00e9gatifs selon les tests mol\u00e9culaires. Ils sont peu co\u00fbteux, rapides et capables d’un d\u00e9pistage rapide et large aux points de soins. Les \u00e9chantillons s\u00e9rologiques par rapport \u00e0 l’\u00e9chantillonnage respiratoire, o\u00f9 les patients sont plus susceptibles de disperser le virus, impliquent un risque plus faible pour le personnel de sant\u00e9.<\/p>\n\n\n\n

En outre, il peut aider \u00e0 \u00e9valuer l’\u00e9tat immunitaire des personnes et \u00e0 estimer l’immunit\u00e9 collective, puisque le plasma convalescent a \u00e9t\u00e9 utilis\u00e9 pour traiter les patients COVID-19 avec un certain succ\u00e8s, les anticorps sont pr\u00e9sum\u00e9s prot\u00e9ger contre le SARS-CoV-2. Parce que les tests s\u00e9rologiques ont \u00e9t\u00e9 \u00e9tablis rapidement et sous les demandes urgentes des march\u00e9s, ils ne sont pas valid\u00e9s dans la pratique quotidienne avec des \u00e9chantillons cliniques (\u00d6z\u00e7\u00fcr\u00fcmez et al., 2020). <\/p>\n\n\n\n

Il existe \u00e9galement un manque de preuves de validation de la part des fabricants de diagnostics in vitro qui ont r\u00e9guli\u00e8rement examin\u00e9 les patients atteints d’infections asymptomatiques. Les tests s\u00e9rologiques, s’ils sont bien valid\u00e9s avec des tests mol\u00e9culaires, peuvent \u00eatre mieux utilis\u00e9s pour \u00e9valuer la pr\u00e9valence r\u00e9elle de l’infection au niveau de la population sans courir le risque de taux inutilement \u00e9lev\u00e9s de r\u00e9sultats faussement positifs. La d\u00e9tection s\u00e9rologique d’anticorps sp\u00e9cifiques du SARS-CoV-2 permettra ainsi d’estimer le nombre r\u00e9el d’infections.<\/p>\n","protected":false},"excerpt":{"rendered":"

Contexte :Le SARS-CoV-2 est extr\u00eamement virulent, comme ses pr\u00e9d\u00e9cesseurs SARS-CoV et MERS-CoV, qui ont d\u00e9clench\u00e9 des \u00e9pid\u00e9mies en 2003 et 2012. La transmission du SARS-CoV-2 en Afrique \u00e9tait initialement lente, avec peu de cas signal\u00e9s en Egypte suite \u00e0 sa premi\u00e8re apparition le 14 f\u00e9vrier 2020. Dans la plupart des pays africains, de nombreux observateurs […]<\/p>\n","protected":false},"featured_media":398,"menu_order":0,"template":"","meta":{"_acf_changed":false,"inline_featured_image":false},"type-projet":[],"class_list":["post-395","projet","type-projet","status-publish","has-post-thumbnail","hentry"],"acf":[],"yoast_head":"\nS\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria - WANIDA<\/title>\n<meta name=\"description\" content=\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ace-partner.org\/wanida\/projet\/sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria\" \/>\n<meta property=\"og:description\" content=\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria\" \/>\n<meta property=\"og:url\" content=\"https:\/\/ace-partner.org\/wanida\/projet\/sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria\/\" \/>\n<meta property=\"og:site_name\" content=\"WANIDA\" \/>\n<meta property=\"article:modified_time\" content=\"2022-10-08T10:15:43+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/ace-partner.org\/wanida\/wp-content\/uploads\/sites\/5\/2021\/10\/DSC_2356-2.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1500\" \/>\n\t<meta property=\"og:image:height\" content=\"1000\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:title\" content=\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria\" \/>\n<meta name=\"twitter:description\" content=\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria\" \/>\n<meta name=\"twitter:image\" content=\"https:\/\/ace-partner.org\/wanida\/wp-content\/uploads\/sites\/5\/2021\/10\/DSC_2356-2.jpg\" \/>\n<meta name=\"twitter:label1\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/ace-partner.org\\\/wanida\\\/projet\\\/sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria\\\/\",\"url\":\"https:\\\/\\\/ace-partner.org\\\/wanida\\\/projet\\\/sero-epidemiologie-du-sras-cov-2-dans-le-nord-ouest-du-nigeria\\\/\",\"name\":\"S\u00e9ro-\u00e9pid\u00e9miologie du SRAS-CoV-2 dans le Nord-Ouest du Nigeria - 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