Projects

DSTN > Projets > SEC FEDGEN

Project investigators

  • ACE CApIC, Nigeria
    • Prof. E. F. Adebiyi, Covenant University, Ota, Nigeria
    • Prof. E. Adetiba, CApIC-ACE, Covenant University, Ota, Nigeria
    • Dr. Joke A. Badejo, Covenant University, Ota, Nigeria
  • ACE MITIC, Senegal
    • Prof. Maissa Mbaye, Gaston Berger University, Senegal
    • Dr. Dame Diongue, Gaston Berger University, Senegal

Other partners

  • Prof Israel Esan Owolabi, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria
  • Dr. Temitayo Ejidokun, Afe Babalola University, Ado-Ekiti, Ekiti State, Nigeria
  • Prof. F.A. Ibikunle, Landmark University, Omu Aran, Kwara State, Nigeria
  • Prof A.A. Adebiyi, Landmark University, Omu Aran, Kwara State, Nigeria
  • Prof. C. Takenga, Université Libre des Pays des Grands Lacs (ULPGL), Goma, Democratic Republic of Congo (DRC)
  • Prof. B. Mushage, Université Libre des Pays des Grands Lacs (ULPGL), Goma, Democratic Republic of Congo (DRC)
  • Saleh Maitala, IBM, West Africa
  • Chukwuma Okpaka, HP (Nigeria) Ltd
DSTN > Projets > SEC FEDGEN

Title: Development of a Secure Federated Genomics Cloud Architecture Towards Precision Medicine in Africa

Project type: Research Project (4 years)

Abstract:
Next-generation sequencing and other high-throughput technologies are currently transforming life sciences and healthcare research globally. Cloud computing has therefore been adopted to cater for high level storage and computational needs of the researchers. Meanwhile, the deployment of the traditional standalone cloud architecture comes with the challenge of limited computation and storage resources at peak periods. To address this, the idea of multiple clouds’ interconnection known as federated cloud was developed to achieve cross-institutional collaborations in storage and computing power. Existing federated cloud architectures published for generic research communities such as the GARR federated cloud, European federated cloud, and Massachusett open cloud are strictly accessible to researchers within the respective geographical domains. The Canada genomic cloud also focuses specifically on genomic based research activities towards precision medicine in Canada. Unlike their counterparts in the developed regions, scarcity of infrastructure for data storage, processing and interpretation is a major limiting factor for discovery, innovation and precision medicine in Africa.  There are some institutions and consortia in the continent with high-performance computational resources. These include the H3Africa/H3Abionet (h3africa.org and h3abionet.org) consortium and WACREN, but at the moment, most of these resources rather operate in silos. Therefore, the goal of this research project is to develop a secure federated genomics cloud architecture for collaborative research, towards precision medicine in Africa. The cloud federation architecture will comprise of hardware infrastructure, open-source software, data security and privacy model, interfaces, and federation protocols. To realize this goal, two Ph.D students will be recruited to work respectively on i) evolving a secure federated genomic cloud (SEC-FEDGEN) architecture and ii) develop a model for data security and privacy in a federated cloud. Proof of Concept (PoC) testbeds will be developed to evaluate and validate the components of the SEC-FEDGEN architecture. Specifically, based on the evolved architecture, genomics cloud testbeds will be set up at four different CApIC-ACE partners’ sites in Nigeria and Democratic Republic of Congo (DRC) using the funding already secured from the World Bank ACE Impact project. These genomics cloud testbeds will be federated to realize a prototype Secure Federated Genomics Cloud (SEC-FEDGEN) infrastructure for precision medicine deployment in Africa. Cloud APIs and services will also be developed based on the data security and privacy model being proposed. For the benefit of this proposal, there is an ongoing effort at H3Africa (a Pan-African bioinformatics consortium) to establish protocols for precision medicine in Africa. Ultimately, the proposed SEC-FEDGEN architecture can serve as a blueprint for setting up federated cloud testbeds or data centers for other research domains. The consortium for this research is composed of CApIC-ACE and CEA-MITIC (with their respective industry and academic partners). This consortium has complementary competencies in HPC, cloud computing, artificial intelligence and cybersecurity, and CApIC-ACE is a member of the H3Africa/H3Abionet. Researchers at CApIC-ACE under the directorship of Prof. E. F. Adebiyi are working on generating genomics data (of African subjects) that underlie malaria, prostate and breast cancers with funding from the ACEImpact project. Analysis of these dataset will be piloted on the SEC-FEDGEN testbed to be set up.

Keywords:

  • Research themes in digital science: Cloud Computing, High Performance Computing, Cybersecurity, Artificial Intelligence
  • Other research themes and application areas: e-Health, Data Science, Big Data Analytics, Software Engineering
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